In settings where vitamin A deficiency is considered a public health problem, the World Health Organization recommends periodic vitamin A supplementation to reduce mortality in infants and young children 6–59 months of age. However, supplementation of younger infants 1–5 months of age, pregnant women and postpartum women has not been shown to reduce early infant mortality. Results of earlier randomized controlled trials (RCTs) on the effect of neonatal vitamin A supplementation (NVAS) for preventing morbidity and mortality had been inconclusive.
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