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David Barker

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Professor David JP Barker, originator of the “fetal origins of adult disease” hypothesis (Barker hypothesis), died aft er a sudden illness on August 27, 2013.He was known for his revolutionary theory that chronic diseases such as coronary heart disease, stroke, type 2 diabetes and cancer – some of the commonest diseases of our time – are caused by nutrition and other environmental factors during fetal life and infancy. He proposed that the prevention of these diseases lay in the care and nutrition of young women. His work opened up a new fi eld of science, the Developmental Origins of Health and Disease (DOHaD), which has shown that plasticity during early development enables the environment to permanently program the body’s metabolism, and thus determine the pathologies of later life. His ideas had a major infl uence on science, from embryology to public health, and set the stage for the global “First 1,000 Days” campaign, which seeks optimal nutrition for women in pregnancy and for children in the first two postnatal years in order to maximize human capital and health.

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Key Details

Year 2013
Authors Caroline Fall, Clive Osmond
Language English
Keywords
DOI https://doi.org/10.52439/OSKZ7431
DOI Number 10.52439/OSKZ7431
ISBN
ISSN

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