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Interactions Between Multi-Nutrients, Vitamin A, Mastitis and HIV

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In 2002, evidence suggested that the rate of transmission of the HIV-1 virus to infants through breast milk was high, and other work by the same authors suggested that treatment with vitamin A increased breastfeeding transmission, although it had no effect on infants‚ Äô mortality at two years. Two publications this year reported studies to investigate the mechanisms behind these observations. Both studies were based on the same randomized controlled trial (RCT) that involved four treatments: placebo, multi-micronutrients (MN), MN plus vitamin A (VA/BC, retinol and -carotene), and VA/BC only, which were received throughout pregnancy and throughout the first two years postpartum. One trial found that the VA/BC treatment increased the detectable viral load by 34% from six months onwards in breast milk The other study found evidence that all three treatments increased sub-clinical mastitis relative to the placebo and the effects of multivitamins did not vary over the postpartum period for either moderate or severe subclinical mastitis This report tries to make some sense out of these surprising findings.

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Key Details

Year 2010
Authors David I Thurnham
Language English
Keywords
DOI https://doi.org/10.52439/SAWW9298
DOI Number 10.52439/SAWW9298
ISBN
ISSN

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