The red pigment lycopene, the most abundant carotenoid in tomatoes, is also found in lesser amounts in guava, pink grapefruit, papaya, and watermelon. Upon consumption, it accumulates in tissues including liver, adrenals, testes, and prostate . Lycopene is a 40 carbon atom, acyclic, open chain polyisoprenoid with 11 conjugated double bonds . All-trans lycopene is the predominant isomer found in plants, but cis isomers are the form most commonly found in human tissues suggesting preferential absorption of cis isomers . Nearly all men will develop some form of prostate cancer if they live long enough . With a 32% mortality rate, prostate cancer is the second most abundant cancer world-wide . North America and Australia, along with parts of South America and Europe, have the highest incidence rates of prostate cancer . Its occurrence is also high in parts of Africa, and Central America. North Africa and Eastern Asia have the lowest age standardized prostate cancer risk rate worldwide . well as the Annual Report 2005, on page 49 of the Newsletter.
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