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Pune Experience

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India is one of the capitals of the world for diabetes and coronary artery disease. At the KEM Hospital Diabetes Unit in Pune, India, we have been actively involved in studying the susceptibility of Indians to these disorders. Our early research described the characteristics of Indian type 2 diabetic patients: younger age and lower BMI but higher waist-hip ratio and higher insulin resistance compared with European patients. This was the beginning of the ‘thin-fat’ Indian concept which provided an explanation for higher susceptibility of Indians to diabetes compared to Europeans despite a lower BMI. Over the past 25 years, we have progressed to define life course evolution of the Indian phenotype through a number of prospective studies and tested the contribution of genetics, epigenetics, nutrition and other environmental factors to this phenotype .

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Key Details

Year 2015
Authors Chittaranjan S Yajnik, Prachi Katre
Language English
Keywords
DOI https://doi.org/10.52439/AQAM8730
DOI Number 10.52439/AQAM8730
ISBN
ISSN

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