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The biological activity of carotenoid metabolites

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It seems only appropriate that this year’s James Allen Olson Memorial Perspectives on Carotenoids Lecture deals with carotenoid metabolites and their biological activity, since it is the 40th anniversary of the publication by Olson and Hayashi on “The Enzymatic Cleavage of β-carotene into Vitamin A by Soluble Enzymes of Rat Liver and Intestine” [1]. In conjunction with the publication of Goodman and Huang in that same year [2], a scheme was proposed for the central cleavage of β-carotene into 2 moles of retinal (Figure 1), as first proposed by Karrer in 1930 [3]. The enzyme was called 15,15’-β-carotene dioxygenase, but as was shown by the elegant work of  oggon and associates, is actually a The biological activity of carotenoid metabolites* Norman I Krinsky,  department of Biochemistry, School of Medicine and the Jean Mayer  SDA-Human Nutrition Research Center on  ging, Tufts University, Boston, MA 02111 18. Haskell MJ, Jamil KM, Hassan F, Peerson JM, Hossain MI, Fuchs GJ, Brown H (2004) Daily consumption of Indian spinach (Basella alba) or sweet potatoes has a positive effect on  total-body vitamin A stores in Bangladeshi men.

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Key Details

Year 2005
Authors Norman I Krinsky
Language English
Keywords
DOI https://doi.org/10.52439/YBGS2548
DOI Number 10.52439/YBGS2548
ISBN
ISSN

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