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The colorful world of carotenoid (vitamin A) metabolism James Allen Olsen Memorial Lecture, CARIG 2007

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The metabolism of the carotenoid-derived retinoids (vitamin A and its derivatives) is a complex field of research. According to the Medline public database, the keyword “vitamin A” appeared in 545 peer-reviewed scientific journals in the last year. This fact clearly underscores the importance of this vitamin for human health. However, it also tells us that writing an overview of vitamin A metabolism is something of a challenge for the author. Therefore, I will only focus on certain aspects of vitamin A metabolism. I will attempt to walk a tightrope by simplifying matters for the interested layman without seriously adulterating the scientific content. Review articles have been cross-referenced for the benefit of expert readers in search of the details. Additionally, I have written this article from the perspective of a former plant biochemist. For such a person, humans are not the pride of creation, but some sort of plantdependent mutants, deficient in the pathways that enable the production of various important organic compounds, including vitamins. Some aspects of the relationship between the metabolism of carotenoids and their derivatives have persisted throughout evolution and can be found in humans. These ancestral footprints in the genomes of animals bear witness to the common origin of living organisms and have stimulated research across evolutionary barriers.

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Key Details

Year 2007
Authors Johannes von Lintig
Language English
Keywords
DOI https://doi.org/10.52439/YFHV9035
DOI Number 10.52439/YFHV9035
ISBN
ISSN

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